Our Research

Mucosal surfaces such as the intestine and respiratory tract represent dynamic ecosystems where host cells, microbial communities, and environmental factors continuously interact. These interactions are essential for maintaining tissue homeostasis, yet their disruption can drive inflammatory and infectious diseases.

 

The Bang Lab investigates the molecular and metabolic mechanisms that govern host–microbe interactions at mucosal surfaces, with a particular interest in how microbial signals, nutrient availability, and epithelial barrier function shape mucosal immunity and microbial ecology.

 

To address these questions, we integrate approaches from immunology, microbiology, metabolism, and molecular genetics, using experimental systems including mouse models, organoids, microbial genetics, and human microbiome analyses.

 

Through these efforts, we aim to uncover the fundamental principles that coordinate host physiology with microbial communities in mucosal tissues.